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Patient-specific 3D printed medication on-demand – Interview with Wei Jiang from Craft Health

Image: Craft Health

Craft Health, a Singapore-based startup founded in 2019 by two pharmacists, focuses on additive manufacturing for pharmaceutical applications. The company has developed a modular 3D printing platform tailored to the needs of compounding pharmacies and healthcare providers seeking to personalize oral medication. Rather than relying on centralized manufacturing and fixed-dose tablets, Craft Health’s system enables on-demand production of patient-specific dosage forms with varied compositions and release profiles. In an interview with 3Druck.com, CEO and co-founder Dr. GOH Wei Jiang discusses how Craft Health’s approach addresses both clinical and technical challenges in personalized medicine.

The platform integrates a proprietary 3D printer, dedicated slicing and control software, a range of printable excipient blends, and a digital database of formulations. These components—referred to as CraftMake™, CraftControl™, CraftBlends™, and CraftDatabase™—allow precise manipulation of active ingredient combinations and release mechanisms, including immediate, delayed, and sustained release. Notably, the printing process avoids heat and UV curing, preserving the integrity of temperature-sensitive compounds.

Craft Health’s technology is intended for point-of-care environments, where clinicians and pharmacists can compound tailored medications in small batches. This capability supports both titrated dosing and combination therapy, particularly in fields like pediatrics, geriatrics, and chronic disease management. The platform also aligns with localized manufacturing strategies, minimizing waste and dependency on complex pharmaceutical supply chains.

Insights from CEO Wei Jiang

In the following interview, CEO and co-founder Dr. GOH Wei Jiang discusses how Craft Health leverages 3D printing to support personalized medicine and patient-centric care. He outlines the company’s approach to on-demand drug manufacturing and highlights key areas where this technology can be applied effectively.

From Craft Health’s perspective, how is 3D printing reshaping the future of personalized medicine and patient-centric care?

From Craft Health’s perspective, 3D printing is a transformational enabler in the shift toward personalized medicine and patient-centric care. Here’s how:

Personalization at Scale

Craft Health’s platform allows medications and supplements to be customized for each individual—not just in dosage, but in release timing, formulation type, and combination of active ingredients. This moves beyond “one-size-fits-all” medications to truly tailored therapies, improving outcomes for patients with complex or chronic conditions.

Simplifying Polypharmacy

Many patients—especially the elderly or those with multiple conditions—take several pills a day. Craft Health’s 3D printing technology can combine multiple drugs or nutrients into a single customized pill, reducing pill burden and improving medication adherence.

Controlled Release Profiles

Craft Health’s proprietary CraftBlends™ allow for precision control over how and when active ingredients are released, enabling multi-phase release (e.g., immediate + sustained) from a single dosage form. This flexibility supports better therapeutic efficacy with fewer side effects and more accurate dosing.

Better Patient Experience

Craft Health offers 3D-printed gummies (CraftDelights™) and granules (CraftBeads™) as alternatives to traditional tablets, improving palatability and ease of use—especially important for pediatric, geriatric, or dysphagic patients.

Empowering Providers and Pharmacies

Craft Health’s platform isn’t just for manufacturers—it empowers clinicians and compounding pharmacies with the ability to produce personalized medications on demand at the point of care, reducing reliance on centralized mass production and improving responsiveness to individual needs. We provide an end-to-end service for clinicians and compounding pharmacies to use our platforms onsite, including training and troubleshooting to reduce any friction in the adoption of our products.

Sustainability and Local Manufacturing

3D printing supports localized, just-in-time production, reducing waste, overproduction, and supply chain dependencies—an important consideration for healthcare resilience and sustainability.

In summary, from Craft Health’s viewpoint, 3D printing is not just a manufacturing innovation—it’s a clinical tool that puts the patient at the center of the healthcare journey. By bridging the gap between digital precision and pharmaceutical personalization, it enables a new era of smarter, simpler, and more human-centric medication.

Which innovations in drug release technology or material science do you consider most transformative in your CraftMake and CraftBlends platforms?

We have done considerable R&D work in our CraftBlends™. We have carefully selected materials from the US FDA GRAS (Generally Recognized as Safe) list. By adjusting the selection and ratios of the different excipients, we are able to achieve:

– a 3D-printable paste that is neither too wet to hold its shape nor too stiff to be extruded, and

– control over the rate of release of the active ingredients.

We have since created an AI-powered library that can match different active ingredients, based on their properties and desired release profiles, to a recommended excipient profile. This allows us to quickly and precisely match new formulations that are 3D printable using our Craft Health ecosystem.

How is Craft Health addressing regulatory or scalability challenges as it moves from R&D to broader clinical or commercial deployment?

Craft Health Co-founder Dr. LIM Seng Han

Our 3D printer is not classified as a medical device; instead, it functions similarly to a tablet press or capsule-filling machine, where we do not alter the chemical composition or structure of the active ingredients. We use no heat or UV curing, ensuring that no harsh elements are introduced to the active ingredients.

For pharmaceutical products, we can test the active ingredients before and after 3D printing to validate that there have been no changes to their chemical content or profile. We can also conduct many of the tests stipulated by the United States Pharmacopeia, providing additional assurance of product quality.

Looking ahead, what do you see as the most promising applications for 3D-printed medicines—whether in pediatrics, geriatrics, or chronic disease management?

We see huge potential in both pediatrics and geriatrics, where multiple dosing or titrations are often required. We also see opportunities in applications such as pain management and hormone replacement therapy, where similarly, multiple titrations are necessary.

Here you can find further information on Craft Health.


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