Home Materials Polyester resin for volumetric bioprinting: BIO INX and Readily3D introduce READYPCL INX

Polyester resin for volumetric bioprinting: BIO INX and Readily3D introduce READYPCL INX

Picture: BIO INX

With READYPCL INX, BIO INX and Readily3D have introduced a new resin for volumetric bioprinting technology that is based on a polyester-based formulation for the first time. The development is aimed specifically at applications in regenerative medicine and tissue engineering, where mechanically resilient and biodegradable structures are required. The material will be presented to a wider specialist audience for the first time at TERMIS-EU 2025 in Freiburg.

Volumetric bioprinting differs fundamentally from layer-based processes, as the entire 3D body is created within a few seconds through the targeted exposure of a light-sensitive resin. The Tomolite system from Readily3D enables resolutions of up to 100 micrometers. This technology allows complex tissue structures to be generated efficiently, which is particularly important in bone and cartilage replacement research.

“Until now, the majority of materials used for volumetric bioprinting have been gelatin-based,” said Paul Delrot, CEO of Readily3D. “However, demand for alternatives like polyesters has grown rapidly, as they open the door to stiffer, more robust applications such as cartilage and bone tissue engineering.”

READYPCL INX complies with the ISO 10993-5 standard for biocompatibility and is completely biodegradable. The formulation is based on the chemical platform of BIO INX, which has already been tested in other processes such as DLP or multiphoton-based lithography.

“The development of READYPCL INX was a logical next step for us,” said Aysu Arslan, CSO of BIO INX. “This resin builds upon our proprietary chemistry platform, already proven in materials like SOLID INX (extrusion), DEGRES INX (DLP), and DEGRAD INX (multiphoton lithography). Bringing this robustness to the high-speed realm of volumetric printing is tremendously exciting.”

“Volumetric bioprinting is one of the most promising breakthroughs in 3D bioprinting—and even in 3D printing at large,” added Jasper Van Hoorick, CEO of BIO INX. “Its non-layered approach, combined with exceptional speed and reproducibility, brings us closer to operating-room bioprinting. The idea of printing replacement tissues like cartilage or bone directly during surgery is becoming increasingly feasible thanks to materials like READYPCL INX.”


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