An interdisciplinary research team from Empa, the University of Zurich, the Zurich University of Veterinary Medicine, and Radboud University in the Netherlands is developing an artificial cornea that could one day replace donor tissue transplants. The project aims to address the global shortage of corneal transplants—currently, only around 100,000 donor corneas are available each year for millions of patients in need.
The foundation of the new implant is a biocompatible hydrogel composed of collagen and hyaluronic acid. This material is designed to replicate the optical and mechanical properties of the natural cornea while preventing immune rejection by the body.
A key feature of the implant is its self-adhesive surface, allowing the artificial cornea to be implanted without sutures. This reduces surgery time and minimizes postoperative complications such as infections or scarring. In a later development phase, the researchers plan to seed the hydrogel with the patient’s own ocular stem cells to promote regeneration of the surrounding tissue.
The project is fully funded by a private foundation that supports early-stage research initiatives. With its approach to creating a customizable, 3D-printed corneal implant, the team aims to provide a long-term alternative to donor tissue—particularly in regions where access to transplants is currently limited.
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